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Why Israel has become an innovative country of Medical Devices?



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Israel, a Middle Eastern country thousands of miles away from China, once again appeared in sight. On the opening day of the first China International Import Expo, the Israeli Ministry of Science and Technology signed a memorandum with the Shanghai Municipal people's Government. The two sides decided to focus on cooperation in the fields of life science, agriculture, energy and environmental protection, represented by brain science. To this end, the two sides will set up a joint laboratory, and co-funding related cooperation projects. Israel's life science industry is showing a rapid growth trend in the global pharmaceutical industry, especially in the field of medical devices, Israel is the world's second largest medical device suppliers, The country's medical device companies account for 53% of the total number of industry companies. Why the small land has given birth to so many medical device companies / why Israel can become the medical device innovation big country, the innovation mechanism of this country has what kind of enlightenment to the medical profession innovation of our country.

The Israeli Model: the difficult Industry chain spawned excellent IP

It has to be said that the performance of Israel in the field of medical devices is excellent, with data showing the world's first and absolute number of the world's first and absolute numbers of medical devices. In the years 1999-2003, the number of Israeli medical equipment patents has reached 20% for several years and is third in the world. In addition to the strong ability to innovate, Israel's medical device entrepreneurship also has an excellent IP effect. From the film and television, the game to the publication, the whole entertainment industry is in the fire of the concept of IP, indeed in the east wind of the Internet, so the industry is developing its own resources, the medical profession is no exception. In our country, the phenomenon of the net-red medical treatment has been existed, but more around the personal IP, such as in the traditional medicine, the patient is inclined to select a certain expert when going to the hospital, and in the Internet medical care, the brand clove garden has released the clove doctor IP system last year, The slogan of the “A city, a doctor.” was made. In fact, the medical field of Israel is also about IP. But unlike the “The Temple is not as big as the Buddha” 's IP in China's medical field, Israel's medical IP is mainly developed around the core technology. In medical devices, most of the technology inventors of Israel are clinicians, who often think about the solution to the problem in the light of the circumstances encountered in clinical practice, and when they have a product design, they will go to a familiar engineer, Co-operation to complete the design of the product prototype and apply for IP immediately upon completion. In this process, the hospital will also be involved and will help those skilled in the art to apply for patents, improve product and docking resources. In the case of per capita, Israel is the country with the largest number of global patent applications and scientific papers. According to the “Global Innovation Index” from 2012 to 2016, the number of patent applications in the framework of the Patent Cooperation Agreement is the 7th, 11th, 11th, 8th and 7th positions of the world, respectively. In addition to the good IP environment in Israel's medical care, the company's emphasis on IP is also very high, and if a business is closed because of bad management, the company's IP is likely to become a resource for many companies. What is more, there will be a start-up company to buy IP, Re-start the business around this IP. As a result, while Israel has two large and well-known biotech start-up companies _ InterPharm and Bio-ThierGeneral, there are many young and smaller businesses. Israel's medical companies are taking the core technology as the IP, taking into account their exit path in the field. It is not like China's medical start-up, it needs to complete a series of links, such as R & D, clinical, market, and sales, and the company in Israel will choose to sell this IP to a multinational company after the clinical trial has been completed. Therefore, Israel's medical device company, in essence, is building the “net red product”, not the brand of the company. According to data published in 2014 by the Israel Risk Capital Research Centre, while there are some of the well-known large-scale enterprises in Israel, such as the ladder of 40,000 employees, as well as more than a thousand employees of Taro and Dexcel, more than 75% of the enterprise's staff will not be more than 25, More than half of the enterprise's staff are less than 10. The core technology is sold as a net red product, because the domestic market capacity of Israel is limited, the corresponding complete industrial chain can not be provided in the face of high and new technology, and because of the politics and other factors, the product developed by the technology can not be sold to the neighboring countries of the Middle East, so, Israeli companies are more inclined to shift core technology to other countries to hatch, one of Israel's best choices. "The “Now, how to come to China, to be in contact with Chinese enterprises, to find creative and cooperative opportunities, has become the business consensus of the Israeli government.” is, as a result, that Israel has a number of “technical intermediary”, including Yislum, the Hebrew University, the YEDA Technology Transfer Company of the Boltzmann School of Science, the Mott Technology Transfer Company of the University of Tel Aviv," the Minister of Science and Technology of Israel, Ophelia Arguis, said. and the T3 technology transfer company of the Institute of Engineering and Technology of Israel, in which Yissum was founded in 1964, and the main technical fields are biotechnology, nanotechnology, pharmacy, etc., At present, 1,200 patents in schools have been managed, and 83 new patents have been registered in 2003, and some 93 patents have been registered in 2004, and the complete technology transfer system has promoted the industrialization of the technological achievements.


The Enlightenment of the Development experience of Israel's Medical and Armament Industry to China


Nowadays, the medical device industry belongs to the strategic emerging industry supported by our country. With the rapid development of economy, the medical device industry in China is developing rapidly, the average annual compound growth rate is about 23.89%. But compared with the international market, the Chinese medical device market still has the huge growth space. Some data show that in the global medical device market, the scale of the medical device market is already comparable to that of the drug market in the same period, while the Chinese medical device market is only 14 percent of that in the same period. Israel has accumulated many successful experiences in the process of innovation in the field of medical equipment, such as increasing investment in research and development, perfecting policies and regulations, promoting plans to attract wisdom, enhancing the innovation vitality of enterprises, establishing industrial parks in colleges and universities, and creating an atmosphere of innovation culture, and so on. These experiences have important reference significance to the development of Chinese medical equipment industry. (1) because of the political and economic resistance of the neighboring countries, the biotechnology products of Israeli start-up companies will skip the neighboring Middle East countries, plus their own small territory, small population, and limited market capacity. Most of its products will be global. Therefore, Esseli's medical equipment industry from the start, very much attention to the use of foreign resources. In the field of research and development, most of Israel's 280 multinational life science research and development centers were set up by foreign companies after acquiring local companies, according to the Economic and Commercial Counsellor's Office of the Embassy in Israel. In 2014, 167 companies in Israel's life sciences industry raised a total of $801 million, with the main source of venture capital coming from foreign investors, according to the Israeli High Technology Industry Research Center. But the local venture capital company's investment is only 13%. The inspiration for our country is that no country can afford to cooperate with its international counterparts in the innovation of medical devices. First, China has become a major exporter of medical devices as global manufacturing capacity shifts and domestic equipment manufacturing capacity improves. According to China's customs statistics, medical device exports reached $38.489 billion in 2015, with a compound growth rate of 11.18% over the past five years. Secondly, China has formed a medical device industry cluster, with high-quality R & D teams and skilled workers, able to complete high cost effective products, and take advantage of cost advantages. It has become a trend to attract multinational enterprises to move technology R & D and other industries into China as a whole. 2Escape from homogenization mantra besides the landing of foreign resources, Israel's emphasis on local innovation is also an important factor in its success. The resulting favorable policies can also effectively support enterprise innovation and the internationalization of high-end products. China's medical device industry has a low concentration, and the Matthew effect is serious. For example, Merry Medical, the largest manufacturer of medical devices in China, recorded sales of more than 9 billion yuan in 2016. However, the scale of tens of thousands of medical equipment enterprises in the tail is generally small, and the homogeneity is serious. However, the small scale of enterprises will lead to insufficient R & D investment and backward equipment, which seriously restricts the independent innovation of medical device enterprises in our country. Resulting in weak competitiveness in the market. Therefore, in order to realize the rapid development of medical equipment industry, we should attach importance to the innovation of enterprises, whether small and micro enterprises, or the development and expansion of leading enterprises, but also need the support of various related systems. Including financial support, policy support and so on. The policy should not only be guided by the general direction, but also gradually introduce local policies, which can further encourage local enterprises to innovate and reduce the investment of people, money and goods in product development.