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In 2018, the most attractive 11 innovative medical devices!



In 2018, the most attractive 11 innovative medical devices!

Digital health (digital health) / mobile medical (mHealth) flourished in 2018. Many researchers are already working on portable, compact, easy-to-use medical devices that could revolutionize medical diagnostics. Recently, Medical Design& Outsourcing, the industry's website, looked at 11 of the most attractive innovative medical devices in 2018, as follows.

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CerebrotechVisor is a volume impedance phase-shifted (VIPS) spectrometer, which can transmit low energy radio waves. When the patient has a stroke, the fluid in the brain changes and the frequency of the radio wave changes, forming the asymmetric radio waves that CerebrotechVisor can detect. The more asymmetrical the waves are, the more serious the stroke is. Compared with standard physical examination, CerebrotechVisor has better potential in identifying large vessel occlusion. The accuracy rate of predicting stroke was 92%, while the accuracy of standard physical examination was only 40%-89%. The researchers believe that if emergency workers can use CerebrotechVisor to evaluate the patient's macrovascular occlusion in a timely manner, The prognosis of stroke patients will be improved. The accuracy of CerebrotechVisor can assist emergency care workers in determining where patients should be treated, and not necessarily all stroke patients must be taken to comprehensive stroke centers.

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Engineers at the University of California, Berkeley, have developed a nerve stimulator that simultaneously monitors and stimulates electrical currents in the brain to help treat patients with neurological disorders such as epilepsy and Parkinson's. The device is a wireless, non-artifact neuroregulatory device that works like a pacemaker. It monitors electrical activity in the brain, emits stimuli when needed, recognizes signs of vibration or epilepsy, and adjusts the stimuli appropriately. In case of any unnecessary operation. Although the device has been tested only in monkeys so far, it has been shown to be able to detect nerve signals and transmit electrical stimuli.

Tattoo-like glucose monitoring sensor

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Researchers at the University of California, San Diego, have developed a convenient glucose-monitoring tattoo sensor that measures insulin levels through sweat on the skin. Like a temporary tattoo, the patch measures blood sugar without pricking the skin. It features patterned electrodes printed directly on temporary tattoo paper.

Noninvasive migraine treatment apparatus

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ElectroCore launched a noninvasive vagus stimulator gammaCoreSapphire. in 2018 The device is the first non-invasive vagus stimulation device approved by FDA for acute migraine and intermittent cluster headache. GammaCore Sapphire is a portable handheld device that enables patients to treat pain according to actual conditions. It has an easily controlled and smooth stimulating surface that is easily placed on the vagus nerve, and an intensity button on the side that adjusts the strength of the treatment and displays state information through the display. The device can be placed above the cervical vagus nerve to stimulate nerve fibers and relieve pain. Unlike painkillers, the device not only has no side effects, but can also treat a variety of headaches according to a doctor's prescription. In addition, the device also has rechargeable and reuse functions, can be used for many years.

Plug and play diagnostic equipment

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MIT researchers developed an assembly block called Ampli. These blocks can be connected by multiple configurations to create different diagnostic devices. The blocks are cheap, costing about 6 cents for four, and do not require refrigeration or special treatment, the researchers said. Ampli blocks can be plug-and-play for a variety of purposes, including blood sugar testing, virus infection and other diseases. At the same time, many biochemical functions can be performed, which can contain antibodies, which can be used to detect different molecules in blood and urine samples. Antibodies are linked to nanoparticles, and when a specific molecule exists, the color of nanoparticles changes. The researchers found that if diagnostic tests were designed as a toolkit containing modular components, they could be combined to create the devices that patients really needed to serve more people who needed them. So far, researchers have created about 40 different blocks that laboratories around the world can assemble themselves, just as in the 1970s people assembled radios and electronic devices using electronic templates.

Gastrointestinal disease diagnosis chip

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MIT researchers have also developed an absorbable sensor. This kind of sensor can be used to diagnose gastric hemorrhage by bacteria, and it is also valuable in the diagnosis of other gastrointestinal problems. The system, known as a "bacterial chip," uses sensors with living cells and ultra-low power electronics to convert bacterial reactions into wireless signals that can be read by smartphones. Studies on bacterial microarrays have shown that the sensors are responsive to both heme and inflammatory markers. So far, researchers have tested the chip on pigs and confirmed that it detects stomach bleeding in pigs. The researchers also hope that the sensor can be used once, or stay in the digestive tract for days or weeks, while sending continuous wireless signals to help patients with gastrointestinal diseases.

Plastic sensor

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Researchers at Cambridge University have developed a plastic sensor to diagnose or monitor health conditions such as surgical complications or neurodegenerative diseases. The sensor, which is inexpensive, measures the content of key metabolites such as lactate and glucose in sweat, tears, saliva or blood. When used with diagnostic equipment, it can quickly and accurately monitor the health status of the body. So far, the device has been designed more simply than other sensors and offers more possibilities for cell-level health monitoring, the researchers said. The sensor is made of a new synthetic polymer developed by Imperial Institute of Technology. These polymers act like a molecular line that directly receives electrons produced in electrochemical reactions. Once the material touches a liquid, such as sweat, blood or tears, it absorbs ions and begins to swell and merge with the liquid. Compared with the traditional metal electrode sensor, the sensor has higher sensitivity. Even in more complex circuits, such as transistors, the signal is amplified and responds to minor changes in metabolite concentrations, even though the device itself is small. It should be noted that the device consists mainly of semiconductor plastics, similar to those currently used for solar cells and some electronic products. However, these plastics are not yet widely used in the biological field.

Mobile app for Detection of Infectious Diseases

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Researchers at the University of California, Santa Barbara, have developed a smartphone called app, that remotely recognizes bacteria in patients, helps doctors diagnose diseases and prescribes antibiotics within an hour. The app uses a phone camera to detect chemical reactions, uses smartphones, hot plates, LED lights and cartons for quick diagnostics, and determines the results within an hour. At present, the system has been able to achieve rapid diagnosis of urinary tract infection. The test is simple and inexpensive, costs less than $100 and can be carried out even in remote areas around the world.

Microspectrometer based on Chip

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MIT researchers have discovered a new affordable way to make spectrometers-spectrometers based on microchips. This method can make the spectrometer produce in a large scale and play a more useful role. The researchers believe the method has advantages over current spectrometers in terms of performance, size, weight and power consumption. The system is based on optical switches, the researchers said. The optical path can flip the beam between different paths in an instant, and the optical path can have different lengths. These all-electron optical switches eliminate the need for removable mirrors needed in traditional spectrometers and can be easily manufactured using standard chip manufacturing techniques. The spectrometer based on chip not only has built-in processing ability, but also can expand the sequence switch from 6 to 10, so that the resolution can be increased from 64 spectrum channels to 1024, which can better control the device and process its output. In addition, as a plug-and-play device, the device can be easily integrated with existing optical networks.

Tumor tracking GPS in vivo

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MIT researchers have developed a wireless system called ReMix, which resembles GPS in the body. It can accurately locate the position of absorbable implants implanted into human body by using low power wireless signal, which provides more possibilities for tumor tracking in patients and the way of drug administration by clinicians. To test the ReMix system, researchers implanted a marker in animal tissue, used a wireless device to track its movement, and used a special algorithm to pinpoint the location of the marker. The results show that the ReMix system can track implants accurately. Researchers believe that similar systems may one day also be used for accurate drug delivery in different parts of the body. ReMix system can be used in proton therapy, including the use of proton beam to expose tumors, and so on. The finding means doctors can prescribe higher doses of radiation, but the accuracy of the method is so high that it inevitably limits its use in patients with some types of cancer.

Wireless power supply system for internal equipment

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Researchers at MIT and Brigham Women's Hospital have developed a wireless system that can power and communicate with devices implanted deep into the human body. The researchers believe the system can be used to deliver drugs, monitor the state of the body, and treat disease by stimulating the brain with electricity or light. Radio waves that can safely pass through human tissues can power implanted devices 10 centimeters deep in one metre of tissue, and because they do not require batteries, they can be made very small. Researchers have now tested a grain-sized sample, but they hope to make the device smaller in the future.