The founder of wet healing
The study of Dr. George Winter animal physiologists began in 1962 with a paper published in 1971.
In 1962, he found that the rate of epithelium formation and scar formation in piglets covered with polyethylene membrane doubled. It is first confirmed that wet and permeable wound dressing speeds up the healing process. First published in < Nature >
The Development History of Wet Healing Theory
In 1958, Odland first found that complete blisters heal faster than blister wounds.
2. In 1962, Dr.George.Winter of the University of London, a British zoologist, found that the rate of epithelialization of pigs covered with polyethylene membranes doubled in speed of superficial epithelium formation and scar formation in young pigs. He proved for the first time that in moist, permeable wound dressing conditions, the epidermal cells are better able to reproduce, migrate, and crawl than dry wounds exposed to air, thus accelerating the wound healing process.
3.In 1963, Hinman and Maibach reported the same findings.
4. In 1963, Hinman conducted a human study to confirm the scientific nature of wet healing.
5. The concept of "wet wound healing" gradually became widely accepted in the 1970 s.
6. In 1972, Professor Robee reconfirmed that clean, unscabbed, moist wounds migrate their epithelial cells much faster than scabbed wounds, because epithelial cells cannot migrate to dry scabbed layers of cells. It took time to move to a wet bed under the crust, and the idea of wettable therapy became widely accepted in the clinic. 7. In the early 1990s, Turner reported that continuous wetting treatment had significantly accelerated wound size reduction, mass granulation formation and rapid epithelial regeneration. 8. Knighton also found that after sealing wound with closed dressing, the basal bed of the wound remained moist and formed hypoxic environment, which stimulated capillary growth and regeneration and became the basis of granulation growth. 9. In 1992, the Wheeland study also showed that there was no callus in moist environment, but eschar could hinder the migration of epidermal cells, because the migration of epidermal cells started mainly from the origin of the wound, and the crusting forced the migration of epidermal cells around the subeschar of the callus, thus prolonging the healing time. 10. In August, 2000, FDA issued a new industry guide to emphasize that keeping wound moist is the standard method of wound management.
Previous: Effect of scar paste on silica gel film